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| Date | Insider | Role | Type | Shares | Price | Value | Chg% | SEC |
|---|---|---|---|---|---|---|---|---|
| 2025-10-15 | Pelish Henry E. | Chief Scientific Officer | Sale+OE | 14,205 | $90.04 | $1,279,018.20 | -17.7% | → |
| 2025-10-14 | Balcom Alexandra | Chief Financial Officer | Sale+OE | 40,000 | $87.36 | $3,494,303.10 | -8.0% | → |
| 2025-10-14 | Pelish Henry E. | Chief Scientific Officer | Sale+OE | 10,070 | $88.84 | $894,577.89 | -3.7% | → |
| 2025-10-01 | Balcom Alexandra | Chief Financial Officer | Sale+OE | 20,000 | $85.48 | $1,709,511.80 | -13.8% | → |
| 2025-09-30 | Balcom Alexandra | Chief Financial Officer | Sale+OE | 27,588 | $85.05 | $2,346,255.88 | -18.3% | → |
| 2025-09-29 | Noci Darlene | Chief Development Officer | Sale+OE | 4,000 | $83.07 | $332,288.05 | -1.6% | → |
| 2025-09-15 | Porter James Richard | President and CEO | Sale+OE | 27,000 | $79.08 | $2,135,055.30 | -3.4% | → |
| 2025-09-10 | Pelish Henry E. | Chief Scientific Officer | Sale+OE | 3,725 | $78.83 | $293,641.75 | -5.3% | → |
| 2025-08-25 | Noci Darlene | Chief Development Officer | Sale+OE | 4,000 | $74.62 | $298,488.74 | -2.7% | → |
| 2025-08-15 | Porter James Richard | President and CEO | Sale+OE | 27,000 | $75.42 | $2,036,325.40 | -3.5% | → |
| 2025-08-07 | Pelish Henry E. | Chief Scientific Officer | Sale+OE | 5,500 | $74.85 | $411,675.00 | -8.3% | → |
| 2025-07-30 | Noci Darlene | Chief Development Officer | Sale+OE | 4,000 | $80.36 | $321,440.00 | -7.7% | → |
| 2025-07-16 | Balcom Alexandra | Chief Financial Officer | Sale+OE | 20,000 | $84.67 | $1,693,496.10 | -6.0% | → |
| 2025-07-15 | Porter James Richard | President and CEO | Sale+OE | 27,000 | $82.27 | $2,221,419.35 | -2.6% | → |
| 2025-07-10 | Pelish Henry E. | Chief Scientific Officer | Sale+OE | 7,645 | $80.31 | $613,985.80 | -3.0% | → |
| 2025-06-27 | Balcom Alexandra | Chief Financial Officer | Sale+OE | 20,000 | $80.02 | $1,600,400.00 | -24.5% | → |
| 2025-06-27 | Pelish Henry E. | Chief Scientific Officer | Sale+OE | 2,170 | $79.92 | $173,426.40 | -3.3% | → |
| 2025-06-26 | Noci Darlene | Chief Development Officer | Sale+OE | 3,915 | $78.74 | $308,248.20 | -3.9% | → |