| 2021-04-14 | Lloyd George W. | EVP, Investments & GC | Sell | 69,822 | $42.13 | $2,941,920.15 | -21.8% | → |
| 2021-04-14 | Reddoch James F. | EVP, Research & Investments | Sell | 55,714 | $42.10 | $2,345,592.83 | -21.8% | → |
| 2021-04-12 | Lloyd George W. | EVP, Investments & GC | Sell | 449 | $42.32 | $19,001.68 | -0.1% | → |
| 2021-04-12 | Reddoch James F. | EVP, Research & Investments | Sell | 359 | $42.32 | $15,192.88 | -0.1% | → |
| 2021-03-22 | Reddoch James F. | EVP, Research & Investments | Sell | 43,927 | $46.32 | $2,034,518.54 | -14.6% | → |
| 2021-03-22 | Lloyd George W. | EVP, Investments & GC | Sell | 54,729 | $46.32 | $2,535,226.28 | -8.7% | → |
| 2021-03-03 | Coyne Terrance P. | EVP & CFO | Sell | 100,000 | $44.78 | $4,478,450.32 | -10.2% | → |
| 2021-03-02 | Lloyd George W. | EVP, Investments & GC | Sell | 125,000 | $46.94 | $5,867,148.21 | -14.2% | → |
| 2021-03-02 | Reddoch James F. | EVP, Research & Investments | Sell | 100,000 | $46.92 | $4,692,158.19 | -14.2% | → |
| 2021-03-02 | Coyne Terrance P. | EVP & CFO | Sell | 100,000 | $46.94 | $4,694,090.14 | -14.2% | → |
| 2021-02-25 | Fernandez Henry A | Director | Buy | 25,700 | $46.83 | $1,203,479.60 | New | → |
| 2020-12-18 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 10% Owner | Sell | 7,301,050 | $43.92 | $320,672,221.00 | -8.6% | → |
| 2020-10-20 | RIGGS RORY B | Director | Sell | 463,200 | $42.00 | $19,454,400.00 | -100% | → |
| 2020-06-18 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 10% Owner | Buy | 3,000,000 | $28.00 | $84,000,000.00 | +7.0% | → |
| 2020-06-18 | Legorreta Pablo G. | CEO, Chairman of the Board | Buy | 20,000 | $28.00 | $560,000.00 | New | → |
| 2020-06-18 | Lloyd George W. | EVP, Investments & GC | Buy | 14,200 | $28.00 | $397,600.00 | New | → |
| 2020-06-18 | Coyne Terrance P. | EVP & CFO | Buy | 2,950 | $28.00 | $82,600.00 | New | → |
| 2020-06-18 | Hite Christopher | EVP & Vice Chairman | Buy | 70,000 | $28.00 | $1,960,000.00 | New | → |
| 2020-06-18 | RIGGS RORY B | Director | Buy | 15,000 | $28.00 | $420,000.00 | New | → |
| 2020-06-18 | FORD WILLIAM E | Director | Buy | 1,500,000 | $28.00 | $42,000,000.00 | New | → |
| 2020-06-18 | Giuliani Mario Germano | Director, 10% Owner | Buy | 50,000 | $28.00 | $1,400,000.00 | New | → |
| 2002-12-12 | RIGGS RORY B | Director | Sell | 40,010 | $41.98 | $1,679,683.82 | -29.3% | → |