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| Date | Insider | Role | Type | Shares | Price | Value | Chg% | SEC |
|---|---|---|---|---|---|---|---|---|
| 2026-01-07 | MacLean Michael F | Chief Financial Officer | Sell | 1,974 | $72.23 | $142,582.02 | -3.0% | → |
| 2026-01-07 | McCarthy Teresa | Chief Human Resources Officer | Sell | 1,965 | $72.23 | $141,931.95 | -1.7% | → |
| 2026-01-07 | Calderaro Charles III | Chief Technical Officer | Sell | 3,727 | $72.23 | $269,201.21 | -7.0% | → |
| 2026-01-07 | Boyce Sarah | President and CEO | Sell | 8,576 | $72.23 | $619,444.48 | -2.9% | → |
| 2026-01-07 | Hughes Steven George | Chief Medical Officer | Sell | 2,373 | $72.23 | $171,401.79 | -6.1% | → |
| 2026-01-07 | Flanagan W. Michael | Chief Scientific Officer | Sell | 2,373 | $72.23 | $171,401.79 | -2.5% | → |
| 2026-01-07 | Moriarty John B | Chief Legal Officer | Sell | 2,374 | $72.23 | $171,474.02 | -3.1% | → |
| 2025-10-22 | Hughes Steven George | Chief Medical Officer | Sale+OE | 2,209 | $47.54 | $105,014.53 | -5.4% | → |
| 2025-10-15 | McCarthy Teresa | Chief Human Resources Officer | Sale+OE | 20,000 | $50.15 | $1,003,058.00 | -17.1% | → |
| 2025-10-03 | Mosbrooker Eric | Chief Commercial Officer | Sale+OE | 6,562 | $45.38 | $297,771.09 | -10.7% | → |
| 2025-09-22 | Hughes Steven George | Chief Medical Officer | Sale+OE | 2,208 | $40.58 | $89,600.64 | -5.4% | → |
| 2025-09-15 | Hughes Steven George | Chief Medical Officer | Sale+OE | 1,542 | $45.41 | $70,022.22 | -3.8% | → |
| 2025-09-15 | McCarthy Teresa | Chief Human Resources Officer | Sale+OE | 15,000 | $41.41 | $621,142.50 | -13.4% | → |
| 2025-09-11 | Flanagan W. Michael | Chief Scientific Officer | Sale+OE | 20,000 | $38.94 | $778,702.00 | -20.0% | → |
| 2025-09-05 | WILSON TROY EDWARD | Director | Sale+OE | 29,500 | $50.00 | $1,475,000.00 | -19.2% | → |
| 2025-09-05 | Boyce Sarah | President and CEO | Sale+OE | 50,000 | $49.95 | $2,497,435.00 | -14.1% | → |
| 2025-09-03 | Mosbrooker Eric | Chief Commercial Officer | Sale+OE | 6,563 | $47.07 | $308,935.50 | -10.7% | → |
| 2025-09-02 | Gallagher Kathleen P. | Chief Program Officer | Sell | 188 | $47.42 | $8,914.96 | -0.4% | → |
| 2025-08-28 | Boyce Sarah | President and CEO | Sale+OE | 25,000 | $49.39 | $1,234,700.00 | -7.6% | → |
| 2025-08-22 | Hughes Steven George | Chief Medical Officer | Sale+OE | 2,208 | $46.40 | $102,461.58 | -5.4% | → |
| 2025-08-15 | McCarthy Teresa | Chief Human Resources Officer | Sale+OE | 10,000 | $46.56 | $465,632.00 | -9.3% | → |
| 2025-08-13 | Hughes Steven George | Chief Medical Officer | Sale+OE | 1,542 | $46.66 | $71,949.72 | -3.8% | → |
| 2025-08-06 | Hughes Steven George | Chief Medical Officer | Sale+OE | 81,434 | $42.74 | $3,480,269.29 | -19.8% | → |
| 2025-08-06 | LEVIN ARTHUR A | Director | Sale+OE | 107,500 | $47.62 | $5,118,881.25 | -84.5% | → |
| 2025-08-06 | Mosbrooker Eric | Chief Commercial Officer | Sale+OE | 130,807 | $44.06 | $5,763,696.52 | -53.0% | → |
| 2025-08-06 | MacLean Michael F | Chief Financial Officer | Sell | 30,914 | $42.73 | $1,320,843.93 | -32.0% | → |
| 2025-08-06 | WILSON TROY EDWARD | Director | Sale+OE | 95,054 | $45.00 | $4,277,430.00 | -11.3% | → |
| 2025-08-04 | Moriarty John B | Chief Legal Officer | Sell | 2,245 | $36.21 | $81,291.45 | -4.5% | → |
| 2025-06-17 | Gallagher Kathleen P. | Chief Program Officer | Sell | 911 | $30.24 | $27,548.64 | -1.8% | → |
| 2025-06-11 | Flanagan W. Michael | Chief Scientific Officer | Sale+OE | 20,000 | $32.88 | $657,694.00 | -20.0% | → |
| 2025-06-02 | Gallagher Kathleen P. | Chief Program Officer | Sale+OE | 5,875 | $32.48 | $190,832.93 | -10.4% | → |
| 2025-05-01 | Gallagher Kathleen P. | Chief Program Officer | Sale+OE | 5,875 | $32.40 | $190,324.15 | -10.4% | → |
| 2025-04-01 | Gallagher Kathleen P. | Chief Program Officer | Sale+OE | 5,875 | $27.83 | $163,485.98 | -5.5% | → |
| 2025-03-20 | McCarthy Teresa | Chief Human Resources Officer | Sell | 7,778 | $31.06 | $241,583.12 | -7.4% | → |
| 2025-03-20 | MacLean Michael F | Chief Financial Officer | Sell | 7,935 | $31.06 | $246,424.60 | -7.6% | → |
| 2025-03-20 | Flanagan W. Michael | Chief Scientific Officer | Sell | 11,780 | $31.06 | $365,867.95 | -12.8% | → |
| 2025-03-20 | Hughes Steven George | Chief Medical Officer | Sell | 9,578 | $31.06 | $297,490.76 | -11.6% | → |
| 2025-03-20 | Boyce Sarah | President and CEO | Sell | 31,540 | $31.06 | $979,563.01 | -9.3% | → |