| 2015-11-30 | KAKKIS EMIL D | President & CEO | Sell | 18,050 | $98.47 | $1,777,329.86 | -1.0% | → |
| 2015-11-23 | AGARWAL SUNIL | Chief Medical Officer | Sell | 498 | $95.88 | $47,748.24 | -3.5% | → |
| 2015-10-30 | KAKKIS EMIL D | President & CEO | Sell | 20,000 | $99.57 | $1,991,407.00 | -0.8% | → |
| 2015-10-20 | AGARWAL SUNIL | Chief Medical Officer | Sell | 649 | $85.51 | $55,495.99 | -4.2% | → |
| 2015-09-22 | AGARWAL SUNIL | Chief Medical Officer | Sell | 498 | $109.51 | $54,535.98 | -3.0% | → |
| 2015-08-20 | AGARWAL SUNIL | Chief Medical Officer | Sale+OE | 17,020 | $111.18 | $1,892,211.88 | -10.6% | → |
| 2015-08-12 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,334 | $109.70 | $365,739.80 | -4.5% | → |
| 2015-07-20 | Sharp Shalini | CFO & Senior Vice President | Sell | 3,854 | $131.95 | $508,532.22 | -2.9% | → |
| 2015-07-20 | Sharp Shalini | CFO & Senior Vice President | Sell | 3,854 | $131.95 | $508,532.22 | -2.9% | → |
| 2015-07-08 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,334 | $102.12 | $340,468.08 | -4.3% | → |
| 2015-06-18 | Sharp Shalini | CFO & Senior Vice President | Sell | 4,000 | $96.08 | $384,339.60 | -4.1% | → |
| 2015-06-17 | Huizenga Theodore Alan | Controller and PAO | Sale+OE | 1,500 | $94.80 | $142,200.00 | -37.5% | → |
| 2015-06-10 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,334 | $88.19 | $294,025.46 | -4.2% | → |
| 2015-05-18 | Sharp Shalini | CFO & Senior Vice President | Sell | 4,000 | $79.43 | $317,720.00 | -8.1% | → |
| 2015-05-13 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,334 | $72.04 | $240,181.36 | -4.2% | → |
| 2015-04-20 | Sharp Shalini | CFO & Senior Vice President | Sell | 4,000 | $62.23 | $248,910.00 | -3.9% | → |
| 2015-04-08 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,333 | $58.02 | $193,380.66 | -4.0% | → |
| 2015-03-18 | Sharp Shalini | CFO & Senior Vice President | Sell | 4,000 | $61.45 | $245,800.00 | -7.1% | → |
| 2015-03-11 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,333 | $56.30 | $187,647.90 | -3.9% | → |
| 2015-02-18 | Sharp Shalini | CFO & Senior Vice President | Sell | 4,000 | $53.98 | $215,935.48 | -3.3% | → |
| 2015-02-11 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,333 | $54.31 | $181,020.90 | -3.7% | → |
| 2015-01-20 | Sharp Shalini | CFO & Senior Vice President | Sell | 4,000 | $51.24 | $204,957.20 | -6.2% | → |
| 2015-01-14 | Kassberg Thomas Richard | CBO & Senior Vice President | Sell | 3,333 | $51.51 | $171,682.83 | -3.6% | → |