| 2021-05-07 | Harris Erik | EVP & Chief Commercial Officer | Sell | 700 | $113.67 | $79,572.07 | -1.3% | → |
| 2021-05-06 | Huang Dennis Karl | EVP & Chief Tech Ops Officer | Sell | 363 | $113.68 | $41,265.84 | -0.9% | → |
| 2021-05-06 | Parschauer Karah Herdman | EVP and General Counsel | Sell | 313 | $113.67 | $35,578.71 | -1.0% | → |
| 2021-05-06 | Pinion John Richard | See Remarks | Sell | 363 | $113.69 | $41,269.47 | -0.7% | → |
| 2021-05-06 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 142 | $113.67 | $16,141.14 | -0.9% | → |
| 2021-05-06 | Kassberg Thomas Richard | CBO & EVP | Sell | 363 | $113.69 | $41,269.47 | -0.3% | → |
| 2021-05-06 | Bedrosian Camille L | EVP and Chief Medical Officer | Sell | 364 | $113.67 | $41,375.88 | -0.9% | → |
| 2021-05-03 | KAKKIS EMIL D | President & CEO | Sell | 30,000 | $107.80 | $3,234,000.00 | -1.3% | → |
| 2021-04-20 | Harris Erik | EVP & Chief Commercial Officer | Sell | 396 | $104.28 | $41,294.88 | -1.4% | → |
| 2021-04-15 | Bedrosian Camille L | EVP and Chief Medical Officer | Sale+OE | 5,000 | $109.09 | $545,450.00 | -11.3% | → |
| 2021-03-08 | Huizenga Theodore Alan | SVP, Controller and PAO | Sell | 3,000 | $120.69 | $362,070.00 | -18.1% | → |
| 2021-03-02 | Harris Erik | EVP & Chief Commercial Officer | Sell | 3,177 | $138.17 | $438,959.02 | -5.3% | → |
| 2021-03-01 | Kassberg Thomas Richard | CBO & EVP | Sell | 4,572 | $138.17 | $631,713.24 | -4.1% | → |
| 2021-03-01 | Pinion John Richard | See Remarks | Sell | 6,198 | $138.17 | $856,377.66 | -11.0% | → |
| 2021-03-01 | Parschauer Karah Herdman | EVP and General Counsel | Sell | 3,970 | $138.17 | $548,534.90 | -11.6% | → |
| 2021-03-01 | Huizenga Theodore Alan | SVP, Controller and PAO | Sell | 732 | $138.17 | $101,140.44 | -4.2% | → |
| 2021-03-01 | Huang Dennis Karl | EVP & Chief Tech Ops Officer | Sell | 4,255 | $138.18 | $587,955.90 | -9.5% | → |
| 2021-03-01 | Bedrosian Camille L | EVP and Chief Medical Officer | Sell | 4,543 | $138.18 | $627,751.74 | -10.4% | → |
| 2021-03-01 | KAKKIS EMIL D | President & CEO | Sell | 30,000 | $141.80 | $4,254,000.00 | -1.3% | → |
| 2021-02-19 | Aliski William | Director | Sale+OE | 7,500 | $149.01 | $1,117,575.00 | -10.2% | → |
| 2021-01-30 | Bedrosian Camille L | EVP and Chief Medical Officer | Sell | 2,243 | $140.36 | $314,827.48 | -6.3% | → |
| 2021-01-15 | Bedrosian Camille L | EVP and Chief Medical Officer | Sale+OE | 25,000 | $139.18 | $3,479,500.00 | -41.1% | → |
| 2021-01-07 | Huizenga Theodore Alan | SVP, Controller and PAO | Sale+OE | 4,000 | $140.65 | $562,600.00 | -20.3% | → |
| 2021-01-04 | KAKKIS EMIL D | President & CEO | Sell | 30,000 | $136.90 | $4,107,000.00 | -1.3% | → |
| 2020-12-09 | Ultragenyx Pharmaceutical Inc. | Director, 10% Owner | Sell | 800,000 | $100.81 | $80,650,635.35 | -14.4% | → |
| 2020-11-02 | KAKKIS EMIL D | President & CEO | Sell | 30,000 | $96.82 | $2,904,600.00 | -1.3% | → |
| 2020-10-30 | Parschauer Karah Herdman | EVP and General Counsel | Sale+OE | 9,903 | $100.12 | $991,488.36 | -29.2% | → |
| 2020-10-28 | Parschauer Karah Herdman | EVP and General Counsel | Sale+OE | 97 | $100.00 | $9,700.00 | -0.4% | → |
| 2020-10-14 | Bedrosian Camille L | EVP and Chief Medical Officer | Sell | 262 | $88.00 | $23,056.00 | -0.7% | → |
| 2020-10-14 | Parschauer Karah Herdman | EVP and General Counsel | Sell | 325 | $88.00 | $28,600.00 | -1.3% | → |
| 2020-10-14 | Kassberg Thomas Richard | CBO & EVP | Sell | 262 | $87.98 | $23,050.76 | -0.3% | → |
| 2020-10-14 | Harris Erik | EVP & Chief Commercial Officer | Sell | 220 | $88.00 | $19,360.00 | -0.9% | → |
| 2020-10-14 | Pinion John Richard | See Remarks | Sell | 262 | $88.00 | $23,056.00 | -0.6% | → |
| 2020-10-14 | Huang Dennis Karl | EVP & Chief Tech Ops Officer | Sell | 262 | $88.00 | $23,056.00 | -0.7% | → |
| 2020-10-14 | Huizenga Theodore Alan | SVP, Controller and PAO | Sell | 146 | $87.98 | $12,845.08 | -0.9% | → |
| 2020-10-14 | Sharp Shalini | EVP, Finance | Sell | 375 | $87.99 | $32,996.25 | -0.4% | → |
| 2020-10-12 | Pinion John Richard | See Remarks | Sell | 2,780 | $94.47 | $262,626.60 | -5.6% | → |
| 2020-10-08 | Parschauer Karah Herdman | EVP and General Counsel | Sale+OE | 10,000 | $95.00 | $950,000.00 | -29.2% | → |
| 2020-10-06 | Parschauer Karah Herdman | EVP and General Counsel | Sale+OE | 10,000 | $90.00 | $900,000.00 | -29.2% | → |
| 2020-09-23 | Parschauer Karah Herdman | EVP and General Counsel | Sale+OE | 10,000 | $85.00 | $850,000.00 | -29.2% | → |
| 2020-09-01 | KAKKIS EMIL D | President & CEO | Sell | 30,000 | $82.63 | $2,478,900.00 | -1.2% | → |
| 2020-08-21 | Aliski William | Director | Sale+OE | 5,000 | $86.57 | $432,850.00 | -8.1% | → |
| 2020-08-17 | Parschauer Karah Herdman | EVP and General Counsel | Sale+OE | 12,370 | $88.43 | $1,093,884.30 | -19.5% | → |
| 2020-08-17 | Sharp Shalini | CFO & Executive Vice President | Sale+OE | 3,521 | $88.48 | $311,531.04 | -1.2% | → |