| 2022-04-28 | George Simeon | - | Buy | 666,666 | $15.00 | $9,999,990.00 | New | → |
| 2022-04-26 | RA CAPITAL MANAGEMENT, L.P. | - | Buy | 2,200,000 | $15.00 | $33,000,000.00 | +39.2% | → |
| 2021-12-01 | Brandenberger Ralph | Sr. VP, Technical Operations | Sale+OE | 4,140 | $15.64 | $64,749.60 | -100% | → |
| 2021-09-29 | HASTINGS PAUL J | Chief Executive Officer | Sell | 8,500 | $27.18 | $231,050.59 | -1.9% | → |
| 2021-09-01 | Brandenberger Ralph | See Remarks | Sale+OE | 4,140 | $32.08 | $132,811.20 | -100% | → |
| 2021-08-05 | Rajangam Kanya | Chief Medical Officer | Sale+OE | 10,000 | $37.28 | $372,800.00 | -100% | → |
| 2021-08-02 | Trager James | Chief Scientific Officer | Sale+OE | 3,600 | $31.53 | $113,508.00 | -7.5% | → |
| 2021-07-01 | Mahmood Nadir | See Remarks | Sale+OE | 6,500 | $31.71 | $206,115.00 | -19.2% | → |
| 2021-06-21 | HASTINGS PAUL J | Chief Executive Officer | Sell | 8,500 | $26.61 | $226,218.50 | -1.8% | → |
| 2021-06-02 | Brandenberger Ralph | See Remarks | Sale+OE | 4,140 | $24.50 | $101,430.00 | -100% | → |
| 2021-05-10 | Mahmood Nadir | See Remarks | Sell | 3,000 | $27.16 | $81,480.00 | -9.5% | → |
| 2021-05-03 | Trager James | Chief Scientific Officer | Sale+OE | 3,600 | $31.64 | $113,904.00 | -3.8% | → |
| 2021-04-01 | Mahmood Nadir | See Remarks | Sale+OE | 3,500 | $32.70 | $114,450.00 | -10.0% | → |
| 2021-03-30 | HASTINGS PAUL J | Chief Executive Officer | Sell | 17,000 | $30.74 | $522,540.49 | -2.3% | → |
| 2021-02-02 | Trager James | Chief Scientific Officer | Sale+OE | 6,400 | $39.25 | $251,228.74 | -4.3% | → |
| 2021-01-25 | Mahmood Nadir | See Remarks | Sale+OE | 5,500 | $48.57 | $267,120.00 | -7.6% | → |
| 2020-07-14 | GLAXOSMITHKLINE PLC | - | Buy | 833,333 | $18.00 | $14,999,994.00 | +36.0% | → |
| 2020-07-14 | New Enterprise Associates 15, L.P. | - | Buy | 666,666 | $18.00 | $11,999,988.00 | +29.8% | → |
| 2020-07-14 | SANDELL SCOTT D | - | Buy | 666,666 | $18.00 | $11,999,988.00 | +29.8% | → |
| 2020-07-14 | Sonsini Peter W. | - | Buy | 666,666 | $18.00 | $11,999,988.00 | +29.8% | → |
| 2020-07-14 | Makhzoumi Mohamad | - | Buy | 666,666 | $18.00 | $11,999,988.00 | +29.8% | → |
| 2020-07-14 | MAKOWER JOSHUA | - | Buy | 666,666 | $18.00 | $11,999,988.00 | +29.8% | → |
| 2020-07-14 | BASKETT FOREST | - | Buy | 666,666 | $18.00 | $11,999,988.00 | +29.8% | → |
| 2020-07-14 | Florence Anthony A. Jr. | - | Buy | 666,666 | $18.00 | $11,999,988.00 | +29.8% | → |
| 2020-07-14 | Novo Holdings A/S | - | Buy | 555,555 | $18.00 | $9,999,990.00 | +24.8% | → |
| 2020-07-14 | RA CAPITAL MANAGEMENT, L.P. | - | Buy | 3,333,333 | $18.00 | $59,999,994.00 | +146.7% | → |
| 2020-07-14 | Flynn James E | - | Buy | 1,000,000 | $18.00 | $18,000,000.00 | +70.4% | → |