KALV

Insider Ownership

Role	Insider	Shares	Value	30d
?	Venrock Healthcare Capital Partners III, L.P.	5.30M	$83.35M	-
CEO	Palleiko Benjamin L	424.5K	$6.67M	-
CEO	Palleiko Benjamin L	416.2K	$6.54M	-
Other	Yea Christopher	223.5K	$3.51M	-
Other	Yea Christopher	221.0K	$3.47M	-

50 transactions · page 6

Date	Insider	Role	Type	Shares	Price	Value	Chg%	SEC
2019-03-27	SVLSF IV, LLC	10% Owner	Sell	88,010	$29.28	$2,576,708.55	-2.2%	→
2019-03-18	SVLSF IV, LLC	10% Owner	Sell	262,470	$26.70	$7,007,949.00	-11.6%	→
2019-03-18	Venrock Healthcare Capital Partners II, L.P.	10% Owner	Sell	500,000	$28.75	$14,375,000.00	-24.5%	→
2019-03-14	Crockett Thomas Andrew	CEO	Sell	3,000	$30.16	$90,483.90	-1.1%	→
2019-03-05	SVLSF IV, LLC	10% Owner	Sell	75,710	$22.96	$1,738,475.96	-1.6%	→
2019-02-21	SVLSF IV, LLC	10% Owner	Sell	214,198	$20.55	$4,401,353.41	-2.8%	→
2019-01-25	Yea Christopher	Chief Development Officer	Sale+OE	5,453	$17.06	$93,015.09	-6.2%	→
2019-01-23	Yea Christopher	Chief Development Officer	Sale+OE	1,902	$17.01	$32,343.93	-1.1%	→
2019-01-16	Feener Edward P.	Chief Scientific Officer	Sell	4,000	$19.55	$78,209.88	-1.9%	→
2019-01-14	Crockett Thomas Andrew	CEO	Sell	10,000	$19.33	$193,328.29	-1.8%	→
2019-01-07	SVLSF IV, LLC	10% Owner	Sell	4,299	$20.25	$87,072.89	-	→
2019-01-02	SVLSF IV, LLC	10% Owner	Sell	29,352	$20.01	$587,242.49	-0.4%	→
2018-12-19	SVLSF IV, LLC	10% Owner	Sell	2,136	$20.02	$42,758.45	-	→
2018-09-10	ORONSKY ARNOLD L	-	Buy	58,824	$17.00	$1,000,008.00	+17.8%	→
2018-09-10	Cha Albert	-	Buy	1,058,824	$17.00	$18,000,008.00	+352.6%	→
2017-10-12	RA CAPITAL MANAGEMENT, LLC	-	Buy	850,000	$8.50	$7,225,000.00	+143.8%	→
2017-10-12	Shah Rajeev M.	-	Buy	850,000	$8.50	$7,225,000.00	+143.8%	→
2017-10-12	ALDRICH RICHARD	Director	Buy	565,065	$8.61	$4,866,961.35	+153.0%	→
2017-10-12	Novo Holdings A/S	10% Owner	Sell	2,534,302	$9.52	$24,136,778.14	-16.1%	→