| 2019-03-19 | Herbert Timothy P. | CEO and President | Sell | 2,947 | $57.04 | $168,096.88 | -1.4% | → |
| 2019-03-08 | ORBIMED ADVISORS LLC | Director | Sell | 358,449 | $57.23 | $20,513,512.43 | -10.0% | → |
| 2019-03-08 | Khuong Chau Quang | Director | Sell | 358,449 | $57.23 | $20,513,512.43 | -10.0% | → |
| 2019-03-07 | Tansey Casey M | Director | Sell | 25,000 | $54.78 | $1,369,395.00 | -11.1% | → |
| 2019-02-20 | Buchholz Richard | Chief Financial Officer | Sale+OE | 2,000 | $56.87 | $113,740.00 | -29.6% | → |
| 2019-02-19 | Herbert Timothy P. | CEO and President | Sell | 15,000 | $57.34 | $860,100.00 | -6.1% | → |
| 2019-02-05 | Erony Joyce | - | Sell | 37,946 | $53.92 | $2,046,135.60 | -5.2% | → |
| 2019-02-04 | Erony Joyce | - | Sell | 52,054 | $53.07 | $2,762,496.08 | -2.3% | → |
| 2019-01-30 | Erony Joyce | - | Sell | 67,021 | $53.10 | $3,559,040.31 | -2.7% | → |
| 2019-01-25 | Erony Joyce | - | Sell | 62,870 | $52.62 | $3,308,317.01 | -1.8% | → |
| 2019-01-22 | Buchholz Richard | Chief Financial Officer | Sale+OE | 6,000 | $54.18 | $325,080.00 | -55.8% | → |
| 2019-01-15 | Herbert Timothy P. | CEO and President | Sell | 15,000 | $48.70 | $730,430.00 | -2.9% | → |
| 2019-01-15 | Ban Randy | Senior VP, Sales and Marketing | Sale+OE | 10,000 | $48.59 | $485,939.05 | -5.8% | → |
| 2018-12-18 | Herbert Timothy P. | CEO and President | Sell | 15,000 | $42.88 | $643,213.00 | -1.9% | → |
| 2018-12-11 | Khuong Chau Quang | Director | Sell | 614,772 | $37.60 | $23,115,427.20 | -25.2% | → |
| 2018-12-11 | Griffin Jerry C | Director | Sell | 1,300 | $37.60 | $48,880.00 | -2.3% | → |
| 2018-12-11 | ORBIMED ADVISORS LLC | Director | Sell | 614,772 | $37.60 | $23,115,427.20 | -100% | → |
| 2018-11-20 | Herbert Timothy P. | CEO and President | Sell | 15,000 | $39.89 | $598,381.60 | -1.8% | → |
| 2018-11-20 | Ban Randy | Senior VP, Sales and Marketing | Sale+OE | 10,000 | $40.37 | $403,738.93 | -4.0% | → |
| 2018-05-07 | Jandrich Steven | Chief Comp Off & VP, Human Res | Buy | 2,050 | $16.00 | $32,800.00 | New | → |
| 2018-05-07 | Ban Randy | Senior VP, Sales and Marketing | Buy | 900 | $16.00 | $14,400.00 | +3.0% | → |
| 2018-05-07 | Buchholz Richard | Chief Financial Officer | Buy | 4,750 | $16.00 | $76,000.00 | New | → |
| 2018-05-07 | Amzak Health Investors, LLC | 10% Owner | Buy | 125,000 | $16.00 | $2,000,000.00 | +9.1% | → |
| 2018-05-07 | ORBIMED ADVISORS LLC | 10% Owner | Buy | 312,500 | $16.00 | $5,000,000.00 | +14.7% | → |