| 2021-01-08 | Wolchko J Scott | President and CEO | Sell | 60,820 | $117.10 | $7,122,216.60 | -3.9% | → |
| 2021-01-08 | Valamehr Bahram | Chief Development Officer | Sell | 6,230 | $117.10 | $729,552.03 | -1.9% | → |
| 2021-01-08 | TAHL CINDY | General Counsel and Secretary | Sell | 6,229 | $117.10 | $729,434.43 | -1.6% | → |
| 2021-01-08 | Shoemaker Daniel D | Chief Scientific Officer | Sell | 6,229 | $117.10 | $729,434.43 | -1.7% | → |
| 2021-01-08 | Redmile Group, LLC | - | Buy | 327,485 | $85.50 | $27,999,967.50 | +2.6% | → |
| 2020-12-17 | Wolchko J Scott | President and CEO | Sale+OE | 20,000 | $91.82 | $1,836,351.72 | -1.2% | → |
| 2020-12-14 | Valamehr Bahram | Chief Development Officer | Sale+OE | 25,000 | $97.78 | $2,444,476.81 | -3.2% | → |
| 2020-11-16 | Shoemaker Daniel D | Chief Scientific Officer | Sell | 25,000 | $51.83 | $1,295,745.71 | -7.4% | → |
| 2020-11-13 | Wolchko J Scott | President and CEO | Sale+OE | 60,000 | $51.87 | $3,112,423.53 | -2.0% | → |
| 2020-11-05 | TAHL CINDY | General Counsel and Secretary | Sale+OE | 70,801 | $50.47 | $3,573,391.76 | -19.0% | → |
| 2020-10-16 | TAHL CINDY | General Counsel and Secretary | Sale+OE | 29,199 | $50.25 | $1,467,211.79 | -22.7% | → |
| 2020-10-01 | TAHL CINDY | General Counsel and Secretary | Sale+OE | 35,000 | $40.74 | $1,426,065.22 | -9.9% | → |
| 2020-09-14 | Valamehr Bahram | Chief Development Officer | Sale+OE | 25,000 | $36.28 | $907,024.39 | -6.2% | → |