| 2022-12-16 | Battaglia Silvana | Executive Vice President | Sale+OE | 9,852 | $167.00 | $1,645,284.00 | -31.4% | → |
| 2022-12-13 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 78,920 | $165.78 | $13,083,695.46 | -7.1% | → |
| 2022-12-12 | Clark Gina | Executive Vice President | Sale+OE | 392 | $166.30 | $65,190.38 | -1.3% | → |
| 2022-12-09 | Donato Leslie E | EVP & Chief Strategy Officer | Sell | 3,014 | $166.12 | $500,685.68 | -30.1% | → |
| 2022-12-08 | Walgreens Boots Alliance, Inc. | 10% Owner | Sell | 5,961,534 | $165.08 | $984,130,032.72 | -15.0% | → |
| 2022-11-07 | Walgreens Boots Alliance, Inc. | 10% Owner | Sell | 13,234,153 | $154.60 | $2,046,000,053.80 | -25.0% | → |
| 2022-11-04 | Mauch Robert P. | Executive Vice President & COO | Sell | 21,802 | $160.00 | $3,488,320.00 | -51.9% | → |
| 2022-10-11 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $141.72 | $1,626,945.60 | -5.3% | → |
| 2022-09-13 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $142.40 | $1,634,752.00 | -5.3% | → |
| 2022-08-30 | Clark Gina | Executive Vice President | Sell | 288 | $146.80 | $42,278.40 | -1.8% | → |
| 2022-08-09 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $144.25 | $1,655,990.00 | -5.3% | → |
| 2022-07-12 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $142.35 | $1,634,178.00 | -5.3% | → |
| 2022-06-14 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $141.22 | $1,621,205.60 | -5.3% | → |
| 2022-05-11 | Krikorian Lazarus | SVP & Chief Accounting Officer | Sell | 4,895 | $160.00 | $783,200.00 | -25.8% | → |
| 2022-05-11 | Walgreens Boots Alliance, Inc. | 10% Owner | Sell | 6,000,000 | $150.00 | $900,000,000.00 | -10.2% | → |
| 2022-05-10 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $159.47 | $1,830,715.60 | -5.3% | → |
| 2022-05-10 | Krikorian Lazarus | SVP & Chief Accounting Officer | Sale+OE | 6,759 | $158.63 | $1,072,190.94 | -15.1% | → |
| 2022-04-12 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $162.11 | $1,861,022.80 | -5.3% | → |
| 2022-03-28 | Clark Gina | Executive Vice President | Sale+OE | 43,704 | $153.71 | $6,717,741.84 | -73.4% | → |
| 2022-03-15 | Battaglia Silvana | Executive Vice President | Sell | 6,820 | $149.96 | $1,022,727.20 | -84.2% | → |
| 2022-03-08 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 11,480 | $144.97 | $1,664,255.60 | -5.3% | → |
| 2022-02-08 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 24,263 | $141.22 | $3,426,420.86 | -10.6% | → |
| 2022-02-03 | Campbell Elizabeth S | Executive Vice President | Sale+OE | 14,034 | $137.89 | $1,935,148.26 | -64.0% | → |
| 2022-02-03 | Krikorian Lazarus | SVP & Chief Accounting Officer | Sale+OE | 11,653 | $138.14 | $1,609,745.42 | -37.9% | → |
| 2022-02-01 | Mauch Robert P. | Executive Vice President | Sale+OE | 44,492 | $137.04 | $6,097,183.68 | -51.4% | → |
| 2022-01-11 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 24,264 | $136.07 | $3,301,602.48 | -10.6% | → |
| 2021-12-15 | COLLIS STEVEN H | Chairman, President & CEO | Sell | 17,168 | $123.45 | $2,119,389.60 | -7.7% | → |
| 2021-12-14 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 24,264 | $123.95 | $3,007,522.80 | -9.8% | → |
| 2021-11-24 | COLLIS STEVEN H | Chairman, President & CEO | Sell | 17,168 | $123.66 | $2,122,994.88 | -7.1% | → |
| 2021-11-16 | COLLIS STEVEN H | Chairman, President & CEO | Sell | 11,664 | $124.66 | $1,454,034.24 | -4.6% | → |
| 2021-11-12 | Clark Gina | Executive Vice President | Sale+OE | 16,027 | $125.83 | $2,016,679.01 | -36.1% | → |
| 2021-11-09 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 24,264 | $125.33 | $3,041,007.12 | -11.6% | → |
| 2021-11-02 | Mauch Robert P. | Executive Vice President | Sale+OE | 41,214 | $125.34 | $5,165,762.76 | -65.4% | → |
| 2021-10-12 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 24,265 | $119.79 | $2,906,704.35 | -11.6% | → |
| 2021-09-20 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 24,265 | $121.90 | $2,957,903.50 | -11.6% | → |
| 2021-09-02 | Krikorian Lazarus | SVP & Chief Accounting Officer | Sale+OE | 17,673 | $124.51 | $2,200,465.23 | -54.4% | → |
| 2021-08-19 | Chou John G. | Executive Vice President | Sale+OE | 6,081 | $117.94 | $717,193.14 | -8.3% | → |
| 2021-08-17 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 12,784 | $120.53 | $1,540,855.52 | -6.5% | → |
| 2021-08-10 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 20,912 | $118.66 | $2,481,417.92 | -10.2% | → |
| 2021-08-06 | Battaglia Silvana | Executive Vice President | Sale+OE | 4,655 | $121.95 | $567,677.25 | -92.7% | → |
| 2021-07-20 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 12,784 | $117.66 | $1,504,165.44 | -6.4% | → |
| 2021-07-19 | Chou John G. | Executive Vice President | Sale+OE | 6,082 | $112.09 | $681,731.38 | -8.3% | → |
| 2021-07-13 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 20,912 | $114.90 | $2,402,788.80 | -10.1% | → |
| 2021-06-18 | Chou John G. | Executive Vice President | Sale+OE | 6,082 | $117.23 | $712,992.86 | -8.3% | → |
| 2021-06-15 | COLLIS STEVEN H | Chairman, President & CEO | Sale+OE | 12,784 | $118.82 | $1,518,994.88 | -6.3% | → |