| 2025-12-08 | Dreyer Scott | EVP & Chief Commercial Officer | Sale+OE | 17,600 | $48.17 | $847,855.20 | -7.6% | → |
| 2025-12-05 | Balice-Gordon Rita J. | - | Sell | 3,650 | $47.03 | $171,673.37 | -6.5% | → |
| 2025-11-12 | Fallon John A. | - | Sale+OE | 34,853 | $47.21 | $1,645,535.60 | -35.0% | → |
| 2025-11-06 | Tupper Colleen | EVP & Chief Financial Officer | Sell | 30,000 | $40.53 | $1,215,753.34 | -10.4% | → |
| 2025-08-29 | Smith Thomas B | EVP and Chief Medical Officer | Sell | 17,478 | $38.42 | $671,576.42 | -19.9% | → |
| 2025-08-18 | Dreyer Scott | EVP & Chief Commercial Officer | Sale+OE | 16,389 | $38.21 | $626,171.25 | -13.7% | → |
| 2025-08-15 | SANTINI GINO | Director | Sale+OE | 5,405 | $37.19 | $201,018.44 | -5.4% | → |
| 2025-08-13 | Dreyer Scott | EVP & Chief Commercial Officer | Sale+OE | 4,861 | $38.03 | $184,880.84 | -4.5% | → |
| 2025-08-13 | Rubric Capital Management LP | 10% Owner | Sell | 25,000 | $37.85 | $946,250.00 | -0.8% | → |
| 2025-08-08 | Freund John Gordon | Director | Sell | 11,659 | $34.36 | $400,640.55 | -33.5% | → |
| 2025-06-09 | Freund John Gordon | Director | Sale+OE | 6,601 | $30.62 | $202,149.02 | -8.5% | → |
| 2025-03-21 | Dreyer Scott | EVP & Chief Commercial Officer | Sell | 20,808 | $30.03 | $624,794.18 | -8.4% | → |
| 2025-03-21 | Tupper Colleen | EVP & Chief Financial Officer | Sell | 7,602 | $30.02 | $228,250.01 | -2.3% | → |
| 2025-03-14 | Tupper Colleen | EVP & Chief Financial Officer | Sell | 977 | $30.00 | $29,313.32 | -0.6% | → |
| 2025-03-14 | Dreyer Scott | EVP & Chief Commercial Officer | Sell | 2,255 | $30.00 | $67,661.05 | -1.8% | → |
| 2025-03-11 | Tupper Colleen | EVP & Chief Financial Officer | Sell | 10,445 | $30.01 | $313,412.67 | -5.9% | → |
| 2025-03-07 | Dreyer Scott | EVP & Chief Commercial Officer | Sell | 5,643 | $30.00 | $169,299.49 | -1.9% | → |
| 2025-03-07 | Tupper Colleen | EVP & Chief Financial Officer | Sell | 3,453 | $30.00 | $103,591.05 | -1.0% | → |
| 2025-03-06 | Dreyer Scott | EVP & Chief Commercial Officer | Sell | 15,387 | $30.00 | $461,671.55 | -10.8% | → |
| 2025-03-06 | Kuhlmann Shirley R. | EVP and General Counsel | Sale+OE | 86,067 | $28.19 | $2,426,633.99 | -17.8% | → |
| 2025-01-10 | Kuhlmann Shirley R. | EVP and General Counsel | Sale+OE | 27,500 | $33.04 | $908,627.77 | -10.1% | → |
| 2024-09-13 | Smith Thomas B | EVP and Chief Medical Officer | Sell | 9,593 | $36.62 | $351,319.64 | -15.1% | → |
| 2024-09-06 | Kuhlmann Shirley R. | EVP and General Counsel | Sell | 20,225 | $38.26 | $773,791.80 | -5.3% | → |
| 2024-06-03 | Kuhlmann Shirley R. | EVP and General Counsel | Sell | 25,000 | $32.57 | $814,180.12 | -8.2% | → |
| 2024-05-28 | Tupper Colleen | EVP & Chief Financial Officer | Sell | 19,710 | $34.21 | $674,367.80 | -13.1% | → |
| 2024-05-24 | Dreyer Scott | EVP & Chief Commercial Officer | Sale+OE | 108,016 | $33.91 | $3,662,548.45 | -30.6% | → |
| 2024-05-14 | BOHLIN GAREN G | Director | Sale+OE | 28,985 | $32.30 | $936,311.15 | -39.3% | → |
| 2024-02-29 | Smith Thomas B | EVP and Chief Medical Officer | Sell | 995 | $36.76 | $36,580.18 | -1.5% | → |
| 2024-02-26 | Dreyer Scott | EVP & Chief Commercial Officer | Sell | 10,000 | $36.43 | $364,270.33 | -3.5% | → |
| 2024-01-16 | Dreyer Scott | EVP & Chief Commercial Officer | Sell | 23,560 | $32.28 | $760,519.16 | -17.5% | → |
| 2023-12-21 | Ciaffoni Joseph | President and CEO | Sale+OE | 4,357 | $30.38 | $132,376.55 | -1.6% | → |
| 2023-12-20 | Ciaffoni Joseph | President and CEO | Sale+OE | 68,768 | $30.18 | $2,075,086.31 | -7.7% | → |
| 2023-11-27 | Kuhlmann Shirley R. | EVP and General Counsel | Sale+OE | 25,600 | $25.78 | $660,014.08 | -17.6% | → |
| 2023-06-26 | Kuhlmann Shirley R. | EVP and General Counsel | Sell | 1,363 | $22.53 | $30,715.07 | -1.1% | → |