| 2026-01-02 | Horn Howard | Chief Financial Officer | Sell | 3,150 | $22.84 | $71,946.00 | -3.3% | → |
| 2025-12-29 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 85 | $34.38 | $2,922.30 | -0.2% | → |
| 2025-12-10 | Horn Howard | Chief Financial Officer | Sell | 3,081 | $36.38 | $112,086.78 | -3.1% | → |
| 2025-10-13 | Horn Howard | Chief Financial Officer | Sell | 7,942 | $31.51 | $250,252.42 | -7.5% | → |
| 2025-09-18 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 64 | $29.17 | $1,866.88 | -0.1% | → |
| 2025-09-12 | Parschauer Karah Herdman | EVP and Chief Legal Officer | Sell | 2,450 | $31.17 | $76,366.50 | -3.2% | → |
| 2025-09-05 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 84 | $31.39 | $2,636.76 | -0.2% | → |
| 2025-06-20 | Sanders Corazon (Corsee) D. | Director | Sell | 2,405 | $37.39 | $89,922.95 | -13.6% | → |
| 2025-05-05 | Crombez Eric | EVP and Chief Medical Officer | Sell | 762 | $37.93 | $28,901.42 | -0.5% | → |
| 2025-03-06 | Horn Howard | Chief Financial Officer | Sell | 1,785 | $40.40 | $72,114.00 | -1.7% | → |
| 2025-03-03 | Crombez Eric | EVP and Chief Medical Officer | Sell | 8,945 | $42.10 | $376,584.50 | -11.1% | → |
| 2025-03-03 | Parschauer Karah Herdman | EVP and Chief Legal Officer | Sell | 12,846 | $42.10 | $540,816.60 | -14.6% | → |
| 2025-03-03 | Pinion John Richard | See Remarks | Sell | 14,439 | $42.10 | $607,881.90 | -11.8% | → |
| 2025-03-03 | Harris Erik | EVP & Chief Commercial Officer | Sell | 15,103 | $42.10 | $635,836.30 | -14.7% | → |
| 2025-03-03 | Kassberg Thomas Richard | CBO & EVP | Sell | 6,028 | $42.10 | $253,778.80 | -2.2% | → |
| 2025-03-03 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 967 | $42.10 | $40,710.70 | -1.9% | → |
| 2025-03-03 | KAKKIS EMIL D | President & CEO | Sell | 98,434 | $42.20 | $4,153,571.40 | -3.4% | → |
| 2025-02-27 | Parschauer Karah Herdman | EVP and Chief Legal Officer | Sell | 2,990 | $42.88 | $128,223.90 | -2.6% | → |
| 2024-12-30 | KAKKIS EMIL D | President & CEO | Sell | 11,727 | $42.23 | $495,231.21 | -0.5% | → |
| 2024-12-10 | KAKKIS EMIL D | President & CEO | Sell | 8,273 | $50.00 | $413,650.00 | -0.4% | → |
| 2024-10-10 | Horn Howard | Chief Financial Officer | Sell | 7,465 | $52.76 | $393,853.40 | -7.5% | → |
| 2024-09-03 | KAKKIS EMIL D | President & CEO | Sell | 20,000 | $55.85 | $1,117,000.00 | -0.9% | → |
| 2024-09-03 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 91 | $56.19 | $5,113.29 | -0.2% | → |
| 2024-08-06 | KAKKIS EMIL D | President & CEO | Sell | 20,000 | $50.17 | $1,003,400.00 | -0.9% | → |
| 2024-07-02 | Sanders Corazon (Corsee) D. | Director | Sell | 584 | $40.98 | $23,932.32 | -4.6% | → |
| 2024-06-12 | Parschauer Karah Herdman | EVP and Chief Legal Officer | Sell | 9,806 | $45.00 | $441,270.00 | -14.5% | → |
| 2024-06-10 | Sanders Corazon (Corsee) D. | Director | Sell | 1,737 | $41.10 | $71,390.70 | -19.3% | → |
| 2024-05-02 | Crombez Eric | EVP and Chief Medical Officer | Sell | 354 | $43.66 | $15,455.64 | -0.7% | → |
| 2024-04-18 | Crombez Eric | EVP and Chief Medical Officer | Sell | 142 | $44.10 | $6,262.20 | -0.3% | → |
| 2024-03-11 | Kassberg Thomas Richard | CBO & EVP | Sell | 11,509 | $49.93 | $574,644.37 | -4.4% | → |
| 2024-03-07 | Fust Matthew K | Director | Sell | 12,195 | $50.88 | $620,442.75 | -16.5% | → |
| 2024-03-01 | Parschauer Karah Herdman | EVP and Chief Legal Officer | Sell | 3,756 | $53.76 | $201,922.56 | -5.3% | → |
| 2024-03-01 | Kassberg Thomas Richard | CBO & EVP | Sell | 1,011 | $53.76 | $54,351.36 | -0.4% | → |
| 2024-03-01 | Harris Erik | EVP & Chief Commercial Officer | Sell | 4,768 | $53.76 | $256,327.68 | -6.6% | → |
| 2024-03-01 | Crombez Eric | EVP and Chief Medical Officer | Sell | 1,238 | $53.76 | $66,554.88 | -2.5% | → |
| 2024-03-01 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 341 | $53.76 | $18,332.16 | -0.8% | → |
| 2024-03-01 | Pinion John Richard | See Remarks | Sell | 4,173 | $53.76 | $224,340.48 | -4.5% | → |
| 2024-02-07 | KAKKIS EMIL D | President & CEO | Sell | 30,000 | $45.00 | $1,350,000.00 | -5.3% | → |
| 2023-12-29 | KAKKIS EMIL D | President & CEO | Sell | 30,000 | $47.87 | $1,436,100.00 | -5.0% | → |
| 2023-10-23 | Kassberg Thomas Richard | CBO & EVP | Sale+OE | 39,878 | $32.78 | $1,307,200.84 | -13.9% | → |
| 2023-10-19 | KAKKIS EMIL D | President & CEO | Sale+OE | 47,853 | $33.52 | $1,604,032.56 | -7.4% | → |
| 2023-09-07 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sale+OE | 2,163 | $40.80 | $88,249.42 | -4.4% | → |
| 2023-09-05 | Harris Erik | EVP & Chief Commercial Officer | Sell | 6,000 | $37.96 | $227,760.00 | -10.5% | → |
| 2023-09-01 | Huizenga Theodore Alan | SVP, Chief Accounting Officer | Sell | 87 | $38.23 | $3,326.01 | -0.4% | → |